March 27, 2025

Honest Review: ProOnezyme Systemic Enzyme Supplement

Discover the Power of ProOnezyme

Unlock Your Body's Full Potential with Proteolytic Systemic Enzymes

If you’re looking for a high-quality systemic enzyme supplement that delivers noticeable results, ProOnezyme by WellnessOne is absolutely worth considering. With a price point of $36.95 for a 30-day supply (and frequent sales bringing it closer to $32.95), this supplement stands out in both value and performance. Available on Amazon, Walmart, and directly from the manufacturer at procelle.com/wellnessone, ProOnezyme is convenient to purchase and well-supported by a loyal customer base.

  • Facebook
  • Twitter
  • LinkedIn
  • Pinterest
  • Amazon
  • Facebook
  • Twitter
  • LinkedIn
  • Pinterest
  • Amazon

Top-Rated Systemic Enzyme Supplements

Pros:

  • Highly Effective: Many users report relief from joint discomfort, bloating, and post-exercise soreness. The enzyme blend helps break down proteins and supports the body’s natural inflammatory response, making it an excellent daily supplement for overall vitality and recovery.
  • Clean Ingredients: One of the most praised aspects of ProOnezyme is its commitment to purity. It’s free from unnecessary fillers, artificial ingredients, or binders — which is a big deal for people with sensitivities or who want a clean supplement routine.
  • Well-Dosed: Each container includes 90 capsules, and three capsules make up one serving. The capsules themselves are medium in size — easy for most people to take with water on an empty stomach.
  • Potent Blend: The formula includes a full-spectrum mix of systemic enzymes like nattokinase (which is systemically better than serrapeptase), seaprose s, protease, and bromelain, among others. These are clinically backed to support inflammation, cardiovascular health, and improved digestion when taken on an empty stomach.
  • Positive Customer Feedback: Across platforms, ProOnezyme consistently receives high ratings. Many long-term users say they’ve tried other enzyme products but continue to come back to this one for its noticeable benefits and dependable quality.

A Few Considerations:

  • May Cause Temporary Discomfort: Due to its high potency and detoxifying effects, some users may experience mild stomach discomfort, especially during the first few days. According to the company, this is rare and typically resolves with dosage adjustment. If discomfort occurs, it’s recommended to start with just one capsule per day, with food, for one to two weeks before increasing to two or three capsules as tolerated. If issues persist, discontinue use and consult a healthcare provider.

  • Timing is Key: For systemic benefits, capsules must be taken on an empty stomach — which some users find a little tricky to remember at first.

  • Natural Smell: The capsules have a natural, earthy smell, which is completely normal and expected with clean, plant-based ingredients.

  • Blood Thinning Effects: ProOnezyme also acts as a natural blood thinner, so if you are on blood-thinning medications or have a bleeding disorder, consult a healthcare provider before starting.

  • Storage Instructions: It should be stored in a cool, dry place under 85°F to maintain potency.

    .

    ProOnezyme Systemic Enzyme Supplement
    ★★★★★

    ProOnezyme stands out for its exceptional ability to alleviate joint discomfort, reduce inflammation, and enhance post-exercise recovery. Its potent blend of enzymes supports the body’s natural inflammatory response, making it an ideal choice for daily wellness.

    ProOnezyme earns high marks for efficacy, purity, and potency. It’s especially well-suited for women in the 30–65+ range.  While it may require a little timing discipline, the results are more than worth it. Highly recommended as a reliable and effective systemic enzyme supplement that delivers what it promises.

    • Joint Support 90% 90%
    • Digestive Health 65% 65%
    • Inflammation Reduction 95% 95%
    • Improve Circulation 90% 90%
    • Detoxification 85% 85%
    • Cellular Debris 85% 85%
    • Improves Enzyme Activity 100% 100%

    Overview of ProOneZyme Ingredients

    Ingredient

    Source

    Primary Action (s)

    Clinical Applications

    Tolerability

    Seaprose S

    Aspergillus melleus (fungal origin)

    • Anti-inflammatory
    • Thins and breaks down mucus (mucolytic)
    • Immunomodulatory
    • Reduces neutrophil infiltration
    • pro-inflammatory cytokines
    • Breaks down mucus
    • Chronic sinusitis
    • Bronchitis
    • Asthma
    • Systemic inflammation

    High—well tolerated, minimal GI effect

    Nattokinase

    Bacillus subtilis (fermented soy)

    • Fibrinolytic
    • Circulatory support
    • Degrades fibrin
    • Enhances endogenous clot breakdown
    • Supports blood flow
    • Cardiovascular health
    • Fibrin regulation
    • Vascular inflammation

    Moderate—caution with anticoagulants

    Bromelain

    Pineapple stem

    • Anti-inflammatory
    • Proteolytic
    • Digestive aid
    • Inhibits prostaglandins
    • Supports tissue repair
    • Modulates immune response
    • Joint inflammation
    • Sports injuries
    • Swelling
    • Post-surgical recovery

    High—generally well tolerated

    Catalase

    Naturally occurring antioxidant enzyme

    • Antioxidant
    • Anti-oxidative stress
    • Converts hydrogen peroxide into water and oxygen
    • Protects tissues from oxidative damage
    • Cellular detoxification
    • Inflammation reduction
    • Oxidative stress defense

    High—produced endogenously in the body

    Peptidase

    Plant-derived

    • Proteolytic
    • Digestive support
    • Breaks long-chain peptides into absorbable amino acids
    • Protein metabolism
    • Digestive efficiency
    • Immune modulation

    High—broad compatibility

    Rutin

    Buckwheat, citrus peels

    • Antioxidant
    • Vascular protection
    • Anti-inflammatory
    • Strengthens capillary walls
    • Reduces oxidative stress
    • Inhibits inflammatory enzymes
    • Varicose veins
    • Vascular integrity
    • Circulatory support

    High—safe at dietary and supplemental levels

    Trace Mineral Blend

    Natural mineral sources

    • Cofactor support
    • Enzyme activation
    • Supplies zinc
    • Manganese
    • Copper
    • and other cofactors required for enzymatic function
    • Enzyme efficiency Metabolic balance
    • Immune and repair support

    High—depends on mineral ratios and dosing

    Key Benefits

    Why Choose ProOnezyme?

    Highly Effective

    Clean Ingredients

    Potent Enzyme Blend

    Positive Customer Feedback

    Joint Discomfort Relief

    $

    Effective Relief

    Supports Digestive Health

    Reduces Inflammation

    Enhances Recovery

    No Artificial Fillers

    Clinically Backed Formula

    Comprehensive Enzyme Blend

    Convenient Purchase Options

    Affordable Pricing

    Trusted by Users

    Consistent High Ratings

    Recommended for Women 30-65+

    Third Party Tested for Purity

    Why Choose ProOnezyme

    Effective Relief

    Experience noticeable relief from joint discomfort and bloating with our potent enzyme blend.

    Clean Formula

    Our supplement is free from artificial additives, ensuring a pure and safe experience.

    Comprehensive Enzyme Blend

    Includes serrapeptase, protease, and bromelain to support inflammation and digestion.

    Positive Feedback

    Highly rated by users for its effectiveness and quality, making it a trusted choice.

    Convenient Purchase Options

    Available on major platforms like Amazon and Walmart, as well as directly from our website.

    Value for Money

    Offers great performance at a competitive price, with frequent sales available.

    What Our Customers Say

    • Facebook
    • Twitter
    • LinkedIn
    • Pinterest
    • Amazon

    “I’ve had knee issues for years. After taking ProOnezyme consistently for three weeks, the stiffness and pain started easing up. I was skeptical at first, but I’m a believer now.” 

    Elaine M., 56

    • Facebook
    • Twitter
    • LinkedIn
    • Pinterest
    • Amazon

    “I love that it’s clean and doesn’t upset my stomach. I feel more mobile and less puffy overall. This is my third bottle, and I plan to stick with it.” 

    Sharon T., 48

    • Facebook
    • Twitter
    • LinkedIn
    • Pinterest
    • Amazon

    “Great product at a fair price. I’ve tried pricier enzyme brands, and this one works just as well, if not better.” 

    Lori R., 63

    Final Thoughts

    Our Verdict on ProOnezyme

    ProOnezyme stands out for its efficacy and purity, making it an excellent choice for those seeking natural support for joint health and inflammation.

    While it requires some discipline to take on an empty stomach, the long-term benefits are well worth the effort.

    Highly recommended for individuals looking for a reliable enzyme supplement that delivers on its promises.

    Discover the Benefits of ProOnezyme Today

    Unlock the potential of a healthier you with ProOnezyme, the systemic enzyme supplement that supports joint health, reduces inflammation, and enhances overall well-being. Join countless satisfied customers who have transformed their lives with this powerful formula.

    0 Comments

    Submit a Comment

    Your email address will not be published. Required fields are marked *

    Related Posts

    Pin It on Pinterest